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GLP1Pick

Sesame vs Ro

Sesame costs $208/mo combined ($59 care + $149 medication, on a 12-month commitment); Ro charges $74/mo membership on a 12-month plan prepaid annually ($149/mo month to month), medication billed separately from $149/mo, about $223/mo in all. We score Sesame 7.0/10 (#26 of 53) and Ro 7.3/10 (#17): Ro comes out ahead, though Sesame has the lower monthly figure.

Sesame from $208/mo combined ($59 care + $149 medication, on a 12-month commitment)

Verified 2026-11-04

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Ro from $74/mo membership on a 12-month plan prepaid annually ($149/mo month to month), medication billed separately from $149/mo

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Sesame is an affiliate partner: we earn a commission if you sign up through this link. Ro is not a partner, and we earn nothing from it. Scores and rank are set the same way for both.

Which is cheaper, Sesame or Ro?

Sesame has the lower monthly figure: $208/mo against $223/mo for Ro (a membership plus the lowest medication price, added up by us). Check the plan length: a monthly figure on a prepaid plan is not the same as a month-to-month price.

 SesameRo
Pricefrom $208/mo combined ($59 care + $149 medication, on a 12-month commitment)Their page, read 2026-11-04from $74/mo membership on a 12-month plan prepaid annually ($149/mo month to month), medication billed separately from $149/moTheir page (ro.co), read 2026-11-04
Price shapeMembership excludes medicationMembership excludes medication
What the price doesn’t sayThis is two charges added together, not one bill: a care fee plus medication from $149/mo billed separately. Sesame publishes three care fees. $59/mo is care on a 12-month commitment ("*Based on a 12-month Success by Sesame commitment"). $99/mo is care on the Month-to-Month Plan ("Billed every month at $99 per month"), which the same page's billing answer says is "Billed every 28 days", so 13 cycles a year rather than 12. $43/mo appears only on Sesame's medication pages, as "Ongoing care" that "Includes video visits, labs, unlimited chat & more", "From $43 per /mo.", and the page does not explain it: no plan or term is attached, and the same Ozempic page says the subscription "starts as low as $59 per month". We use the $59 and $99 the weight-loss page explains, so the no-commitment floor is $248/mo. On the 12-month plan the care fee is "Billed once every 12 months", so $708 up front. The $149 medication floor is the Wegovy pill at its two lowest doses ("$149/mo. for lower doses (1.5mg, 4mg) or $299/mo for higher doses"), so the bill rises as the dose goes up. Sesame also says its providers "set their own prices", so some may charge more than $59.$74/mo is the Ro Body membership alone on a 12-month plan paid up front once a year; month to month it is $149/mo ($39 for the first month). Medication is billed on top, priced by dose: the Wegovy pill is $149/mo at 1.5 mg and $299/mo at 9 mg and 25 mg, so the lowest total is about $223/mo on the annual plan.
Billed on topThe $59/mo care fee excludes medication entirely; medication starts at $149/mo and is billed separately.Their page, read 2026-11-04Medication is billed separately from the membership, at Ro's cash prices: Wegovy pill from $149/mo, Foundayo pill from $149/mo, Wegovy pen from $199/mo for the first two months, Zepbound KwikPen from $299/mo.Their page (ro.co), read 2026-11-04
Score7.0/10, #26 of 537.3/10, #17 of 53

Which drugs do Sesame and Ro prescribe?

Both sell brand-name drugs: Sesame lists Wegovy, Wegovy pill, Zepbound and Foundayo orforglipron tablet, Ro lists Wegovy pill, Wegovy pen, Zepbound, Foundayo pill and 2 more.

Sesame

brand-name Wegovy, brand-name Wegovy pill, brand-name Zepbound, brand-name Foundayo orforglipron tablet.

Offers oral/sublingual where Ro does not.

Read 2026-11-04

Ro

brand-name Wegovy pill, brand-name Wegovy pen, brand-name Zepbound, brand-name Foundayo pill, brand-name Ozempic, brand-name Saxenda.

Nothing Sesame does not also offer, on the routes we record.

Read 2026-11-04

Can you cancel Sesame or Ro any time?

Sesame

Committed term. The rate applies combined ($59 care + $149 medication, on a 12-month commitment). What happens after the first period: Explicit renewal language: "then $349/mo after", plus the billing terms. "Billed every month at $99 per month", "Billed every 3 months", "Billed every 6 months". (Read at source 2026-09-18.).Their page, read 2026-11-04

Not published. The page does not say what the figure covers.Their page, read 2026-11-04

Ro

The page does not state whether a term is required.Their page (ro.co), read 2026-11-04

Not published. The page does not say what the figure covers.Their page (ro.co), read 2026-11-04

Who each one suits

Sesame

  • Only one of the two offering: oral/sublingual.Basis: published treatments, by drug and route
  • Scores clearly higher on pricing (6.5 vs 5.5).Basis: our published scoring rubric

Ro

  • Scores clearly higher on transparency (7.5 vs 6.0).Basis: our published scoring rubric

So which should you pick?

On our published rubric Ro scores higher (7.3/10, #17 of 53). If the lowest monthly figure matters most, Sesame costs less. Read each full review before you sign up: Sesame review, Ro review, or see the full ranking.

25 of the 53 clinics we rank are an affiliate partner. Scores come only from our published methodology. At equal displayed scores, active affiliate partners are listed first. What it changes is which clinic a promoted button points at, and every such link carries a PICK badge in the table so you can see it before you click.

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Every figure on this page comes from the clinic’s own pages, with the date we read it. We completed no intake.